The most common question asked by our patients is, “How successful is ovulation induction with artificial insemination?” Clearly, there are many variables that factor into the answer of this question. The first thing that must be recognized is that ovulation induction with IUI is meant to improve a woman’s or couple’s chance of successfully conceiving a pregnancy when they are experiencing some form of infertility or sub-fertility. This concept means that women who are ovulating regularly with no significant fertility issues should successfully conceive within 6 months to 1 year depending on their age. If they do not, then the assumption is that some degree of infertility exists. For those who undergo a comprehensive diagnostic evaluation with no specific findings, a diagnosis of unexplained infertility is given.
The goal of ovulation induction with IUI as a treatment is to restore a woman’s fertility to the rate expected of someone her age if there were NO recognized issues of infertility. In general, this means that women through age 30 should achieve pregnancy on average 20-25% per month. Women 30-35 would have a slightly lower monthly success rate of 15-20% per month and those between ages 35-40 roughly have a 10-15% success rate per month. Women above age 40 drop considerably to below 10% with increasing risks of miscarriage as age increases.
Therefore, the maximum success rate that a woman could expect to achieve using fertility medications and IUI would be similar to their age specific success rate. In general, for Clomid with IUI this would range between 12-19% per month and with injectable gonadotropins with IUI this would range between 15-21% per month.